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Blood analysis for parasites

Parasites that live in the human body cause discomfort of an unclear etiology.It can be skin rashes, flatulence, stomach acidity, nausea, weakness, anemia, joint pain.To clarify the diagnosis, special tests must be performed.

Parasites that can live in the human body

We have timets of blood for parasites

Classification of parasites in their appearance:

  1. Lamblia,
  2. Opistorchi,
  3. Echinococci,
  4. Toxockers,
  5. Trichinella,
  6. ASKARIDS.

For the representatives of some professions (for catering companies, children's institutions), worm eggs analysis is required in the design of sanitary books.Children pass the same analysis when entering the kindergartens and a nursery or in a sports section.

  • A classic study on worms living in the gastrointestinal tract is an analysis of the feces and a scraping of the mucosa of the rectum.
  • But there are several more effective blood analysis options for parasites, as planned and according to the method.

Classic worm research

A classic study on worms that live in the gastrointestinal tract (gastrointestinal tract), for example, pins, ascáures worms, is a feces analysis and a scraping of the mucosa of the rectum.But a unique analysis of feces may not show positive results, therefore, it is advisable to do three times.

  1. To analyze the feces and the scraping, the histological coprogram method is used (seeing the cuts of the material under the microscope).The efficiency of the investigation is approximately 20%, because the probability is low that the eggs or the parasite larvae fall into the analyzed material.
  2. The controversial studies for helminths, simple parasites and fungi in the body are electroacupuncture methods.Its essence is to obtain results using measurements of bioelectric reactions of active points with electrodes.For this purpose, special devices are used.Many doctors perceive skeptical research data.
  3. The most informative examination of parasites is a blood test.

Types of Blood Analysis for Parasites

There are several options for blood tests for parasites: as planned and according to the method.Each of these methods has its own advantages and disadvantages.Depending on the methodology used, there are the following types of blood analysis:

  1. Elisa or immunophynticnae of blood;
  2. PCR or polymerase chain reaction;
  3. We haveaning;
  4. Serological blood analysis.

Elisa, antibody and immunoglobulin analysis

This analysis is based on the immune response of the body, the level of its protective reaction to the invasion of parasites.When antibodies are formed in the form of the human body in response to the entrance of a pathogen or simply a strange protein in their blood, they are called immunoglobulins.

  • Using Elisa's results, you can determine the presence of helminths in the body and its type.The precision of the study is much greater than the analysis of the feces.
  • The method is based on the calculation of antibodies in the body to one or another type of parasites, the determination of its connection with strange antigens (immune response) and the enzymatic reaction of the body.
  • Antibodies: Antigens indicate the presence of infection.
  • A blood analysis of Elisa has precision, according to different experts, from 60% to 90% even at the low level of invasion.
  • The advantage of the method, in addition to a high level of precision, is that an immunomanfunction analysis can be monitored by the dynamics of the disease over time.

IFA Blood Makers for Parasites

An antibody analysis seems like a set of characters that denote these antibodies or are called immunoglobulins.

  • In total, 5 of them have been studied: IgG, IgA, IGM, IGE IGD.
  • In practical medicine, the first four immunoglobulin are important.

IGM is the main marker for the acute phase of the disease

IGM: Immunoglobulin, which appears in the acute phase of the disease, indicates the beginning of the infection.

  • Appears in the blood on the fifth day,
  • It is detected by analysis after 6 weeks.
  • Then it begins to disappear quickly.

IGE - Marker, Parasites infection indicator

IGE - Immunoglobulin indicates the presence of parasites or allergies in the human body.

  • It is a process score associated with allergies,
  • Little in the blood circulates, it is based on mucous membranes, macrophages and basophils,
  • Participate in immune responses to infection with parasites.

IgG - Disease and immunity marker

IgG - Immunoglobulin, appears in the disease process.

  • IgG also retained after a cure, for some infections for life, for example, measles, rubella and others.
  • The detection of blood immunoglobulins says that the body had already encountered this infection before, with this specific pathogen.

The result of the Elastic Pair analysis

For different combinations of advantages and disadvantages in the blood test for parasites, you can get the following conclusions:

  1. Lack of infection: all antibodies with one less;
  2. Acute-EG (+/-), IgA (+\), IGM (+);
  3. Chronic form -gg (+/-), IgA (-), IGM (-);
  4. the presence of immunity -igg (+), IgA (-), IGM (-);
  5. Exacerbation of a chronic disease - IgG (+), IgA (+), IGM (+)
  6. If the disease is detected and deemed, then the values less of all the antibodies will be achieved only six months after the course of the treatment, sometimes after 1-2 years.

Elisa's reliability

The ELISA method provides the 90% reliability level for the diagnosis of ascárides infection, plug worms (eterniobiosis), toxocares and others that cause the formation of IgG immunoglobulin in large quantities.

  1. You can determine lambliosis by separate and general value (OPD) of the level of antibodies in the blood.
  2. OPD's value is more than 1 suggests that there is an infection or was,
  3. With a value of less than 0.85 there is no Lamblia.
  4. If the value is in the interval, then it is advisable to repeat the analysis after 2 weeks.

This method is characterized by a series of weaknesses.The analysis allows you to determine the level of antibodies developed in the body for the neutralization of the helminths, and not the worms themselves.

  • Therefore, it is possible to obtain false and false negative results.
  • This also happens when patients taking drugs,
  • Metabolic disorders and the presence of parallel of current chronic diseases.

General Blood Analysis, Changes in parasitic infection

You can indirectly suspect the presence of invasion doing a general blood analysis.Since the presence of worms affects internal organs, the products of their vital activity enter the bloodstream, changing their composition.Partial list of the results of the invasion effect on blood parameters:

  • Increase in hemoglobin;
  • Non -regulatory indicators of ESR;
  • excess eosinophils in 20%;
  • Zhelezia anemia.

If there are no other reasons for such deviations, it is advisable to include a special blood test, Elisa, PCR in the diagnostic program.

Polymerase chain reaction, PCR analysis

The PCR method, or the reaction in the polymers chain, is considered fundamental in the molecular diagnosis and is one of the most modern and precise for the diagnosis of the presence of parasites in the body.

  • It consists of detecting DNA and RNA traces, which belong to parasitic ways of life.
  • The essence of the polymerase reaction is the treatment of blood in such a way that the DNA, the RNA of foreign organisms to a concentration that allows them to determine.

Serological blood analysis

At the same time, the analysis is used as a source of information from the blood serum.

  • Immunogenic antibodies of parasites are investigated.
  • The analysis allows you to identify a large number of parasitic forms, but it does not allow you to determine the invasion stage.
  • Like the IFA method, serological analysis is indirect for diagnosis.
  • If the OPD values are high, it is advisable to also pass the fecal analysis.

Diagnosis by blood exploration method

During the parasites, a drop of "living" blood of a patient is studied by optical devices in which, in addition to worms, it can determine their larvae and fungi.

How to make a blood test for parasites

Elbow vein blood fence

The blood donation for parasites is carried out in a specialized laboratory.The blood for the analysis is taken from the elbow vein in the amount of 3-5 ml and is placed in a dry sterile test tube.Before passing the analysis, it is recommended:

  1. Do not eat for 8 hours;
  2. At dinner, he leaves fatty dishes and milk;
  3. Do not drink alcohol and carbonated drinks;
  4. Avoid excessive physical effort, physiotherapy, radiation x -ray;
  5. refuse to take medications.
  6. The abundant drink is welcome.
  7. The conditions for the donation of blood to PCR are less strict, because the degree of satiety does not affect the presence of DNA of the parasites.

Analysis dates

  • The results of the IFA and serological tests are broadcast within a week.
  • For PCR blood tests and we haveaning, a couple of hours are enough.
  • With the result of the analysis, you should definitely consult a doctor.